Senior Researcher at Institute for Basic Science, South Korea
Ki Jung Kim, Ph.D., is a Senior Researcher at the Center for Cognition and Sociality at the Institute for Basic Science, located in Daejeon, South Korea. With a strong academic foundation in genetic engineering, neuropharmacology, and neurobiology, Dr. Kim has developed expertise in the dynamics of neuro-glial-vascular interactions, with a particular focus on the mechanisms underlying vascular cognitive impairment and neurodegenerative diseases. His research spans across diverse methodologies, including advanced animal models and in vitro approaches, to unravel the complex cellular communication between neurons, astrocytes, and blood vessels in the brain.
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Education
Dr. Kim earned his Bachelor of Science in Genetic Engineering from KyungHee University, South Korea, in 2000. He went on to complete a Master of Science in Neuropharmacology at the Catholic University of Korea’s College of Medicine, where he worked under the mentorship of Prof. Ki-Wug Sung. His doctoral research, also at the Catholic University of Korea, culminated in a Ph.D. in Neurobiology in 2009, where he continued under the guidance of Prof. Sung, further solidifying his expertise in brain function and neurovascular coupling.
Experience
Dr. Kim began his research career as a Research Assistant in the Department of Pharmacology at Catholic University of Korea, where he contributed to numerous projects exploring neuropharmacology. From 2009 to 2019, he served as a Postdoctoral Associate and later as a Senior Research Associate at the Department of Physiology at the Medical College of Georgia, Augusta University, USA. During this time, Dr. Kim focused on vascular cognitive impairment and the neurovascular unit’s role in brain function. In 2021, he joined the Institute for Basic Science as a Senior Researcher, where he continues his investigation into brain function and vascular health, specifically looking at the impact of astrocyte activity in neurodegenerative diseases.
Research Interest
Dr. Kim’s research primarily investigates neurovascular coupling, focusing on how astrocytes contribute to the regulation of blood flow and neuronal activity in the brain. His work seeks to better understand the pathophysiology of vascular cognitive impairment, Alzheimer’s disease, and other neurodegenerative conditions. By using mouse models and advanced imaging techniques, Dr. Kim aims to elucidate the role of astrocytes and endothelial cells in maintaining brain homeostasis and how their dysfunction contributes to disease. His research combines elements of neurobiology, pharmacology, and vascular biology to address key questions in neurodegenerative disease mechanisms.
Award
Dr. Kim has received numerous accolades throughout his career, including being part of pioneering teams recognized for their work in neurovascular coupling. He has been cited widely in the field and has contributed to several highly regarded publications, including those in journals such as Neuroglia, Exp Neurobiol, and GeroScience. Dr. Kim’s work has been acknowledged for advancing our understanding of vascular cognitive impairment and neurodegenerative diseases, making him a respected leader in his field.
Publication
Dr. Kim’s research has led to several influential publications, including:
Kim, K.J., Lee, J.H., Lim, J., et al. (2025). Astrocyte‐Specific Phenotyping of FAD4T as an Alzheimer’s Disease Mouse Model. Glia.
Lee, Y., Reva, M., Kim, K.J., et al. (2025). Distinct modes of dopamine modulation on striatopallidal synaptic transmission. BioRxiv.
Kim, K.J., Patterson, R.E., Diaz, J.R., et al. (2024). Dynamic Neuro-Glial-Vascular Responses in a Mouse Model of Vascular Cognitive Impairment. Neuroglia.
Joo, J., Kim, K.J., Lim, J., et al. (2024). Generation of astrocyte-specific BEST1 conditional knockout mouse with reduced tonic GABA inhibition. Exp Neurobiol.
Nam, M.H., Ko, H.Y., Kim, D., et al. (2023). Visualizing reactive astrocyte-neuron interaction in Alzheimer’s disease. Brain.
Kim, K.J., Diaz, J.R., Presa, J.L., et al. (2021). Decreased parenchymal arteriole tone in a mouse model of vascular cognitive impairment. GeroScience.
Ramiro-Diaz, J.M., Kim, K.J., Brands, M., et al. (2019). Augmented astrocyte microdomain Ca2+ dynamics and parenchymal arteriole tone in angiotensin II-infused hypertensive mice. Glia.
Conclusion
Dr. Ki Jung Kim’s work at the Institute for Basic Science has significantly advanced our understanding of the neurovascular unit’s role in brain health and disease. His expertise in neurovascular coupling and its implications for conditions such as Alzheimer’s and vascular cognitive impairment has positioned him as a key contributor to the field. With numerous publications, international presentations, and ongoing research, Dr. Kim’s career continues to have a profound impact on the scientific community’s understanding of brain function and neurodegenerative diseases.